Chev Chelios (Jason Statham), has survived the fall from a helicopter that occurred at the end of the first movie. Immediately after his fall, he is abducted off the ground by a group of Chinese medics, who take to farm his organs. However, Chev wakes up mid-surgery and sees them take out his heart and replace it with a mechanical one. He then wakes up and kills the operators, but must chase after his heart which has been stolen. He then runs into his old girlfriend Eve Lydon (Amy Smart) who believed him to be dead. [D-Man2010]

The uber-assassin Chev Chelios (Statham), having survived his death fall at the end of the first movie, finds himself still alive, but a Chinese mobster has replaced his heart with a battery-operated ticker. As Chelios tries to hunt down his enemy, he must also occasionally "recharge" his mechanical heart with jolts of electricity to keep himself alive.

	Jason Statham	...	Chev Chelios
	Amy Smart	...	Eve
	Dwight Yoakam	...	Doc Miles
	Efren Ramirez	...	Venus
	Reno Wilson	...	Orlando
	Keone Young	...	Don Kim
	Art Hsu	...	Johnny Vang
	Joseph Julian Soria	...	Chico
	Ling Bai	...	Ria
	Clifton Collins Jr.	...	El Huron
	David Carradine	...	Poon Dong
	Corey Haim	...	Randy
	Geri Halliwell	...	Karen Chelios
	Billy Unger	...	Young Chev
	Jamie Harris	...	Talk Show Host